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Identified genes for preeclampsia during pregnancy


If you are or have ever been pregnant, you surely know what pre-eclampsia is.

Is illness typical of pregnancy, which affects almost 1 in 10 pregnant women, and which usually appears around 20 weeks of gestation, may, from now on, be more controlled thanks to a study that reveals and identifies genetic errors that increase a woman's risk suffer it during pregnancy. Identified the genes of the preeclampsia during pregnancy.

What until now was only a suspicion and speculation, has been confirmed in research carried out by scientists at the University of Washington and supported by the DNA analysis than 310 pregnant women. Of these, 60 were healthy but were hospitalized after presenting severe preeclampsia and the other 250 were hospitalized for complications, and of them 40 also had pre-eclampsia.

The errors detected in the MCP, factor I and factor H genes play an important role in the regulation of the immune response and are what could explain its possible link with pre-eclampsia.

Preeclampsia is related to a arterial vasoconstriction which can cause a decrease in the flow of blood to important organs of the mother such as the kidneys, liver, brain and placenta. With that the arrival of food is reduced and oxygen to the baby, compromising intrauterine growth and decreasing the volume of amniotic fluid.

There are cases when it can cause premature detachment of the placenta, representing risks to the baby's health.

The degree of a preeclampsia is measured based on blood pressure level and of the loss of proteins in the urine that the pregnant woman presents.

Women suffering from arterial hypertension, diabetes, autoimmune diseases (lupus erythematosus), have a multiple pregnancy or are older, will be more likely to develop this disease. Although they may go unnoticed, symptoms of preeclampsia can be identified by severe and persistent headaches, inflammation and swelling of the hands and eyelids, accumulation of fluids in the arms, feet, ankles and legs, alterations in vision (intolerance to light, blurred vision ...) and abdominal pain with vomiting or nausea, in pregnant women.

The way to detect the disease is by Control of blood pressure in all prenatal visits and a urine study to detect protein (proteinuria). For this reason, a good obstetric control and attend all consultations. Until now, the only solution for pre-eclampsia is induction of labor, which can pose a lethal risk to both mother and baby. The earlier this disease occurs, the greater the risks for both of you.

Now that it is known that women who suffer autoimmune diseases are at greater risk of developing this disease, the only thing left, according to scientists, is to drive this relationship to new ways to detect the risk of pre-eclampsia. It is intended to expand research with more pregnant women and the role of other genes in the development of this disease.

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Video: Pre Eclampsia - Overview pathophysiology, presentation, treatment (December 2021).